From: Heng Li Date: Sun, 8 May 2011 03:59:17 +0000 (-0400) Subject: use integer gmax; code cleanup X-Git-Tag: ksprintf-final~30 X-Git-Url: http://www.kaiwu.me/postgresql/commit/static/gitweb.js?a=commitdiff_plain;h=3f2b354fcc4d4fc00bbf6f90a465983e4e1b5f04;p=klib.git use integer gmax; code cleanup --- diff --git a/ksw.c b/ksw.c index 510f456..aa0e160 100644 --- a/ksw.c +++ b/ksw.c @@ -80,9 +80,9 @@ ksw_query_t *ksw_qinit(int p, int qlen, const uint8_t *query, int m, const int8_ int ksw_sse2_16(ksw_query_t *q, int tlen, const uint8_t *target, ksw_aux_t *a) // the first gap costs -(_o+_e) { - int slen, i, sum, score, m_b, n_b, te = -1; + int slen, i, sum, m_b, n_b, te = -1, gmax = 0, _thres = 254 - q->mdiff; uint64_t *b; - __m128i zero, gapoe, gape, shift, gmax, reduce, thres, *H0, *H1, *E, *Hmax; + __m128i zero, gapoe, gape, shift, reduce, thres, *H0, *H1, *E, *Hmax; #define __max_16(ret, xx) do { \ (xx) = _mm_max_epu8((xx), _mm_srli_si128((xx), 8)); \ @@ -94,11 +94,11 @@ int ksw_sse2_16(ksw_query_t *q, int tlen, const uint8_t *target, ksw_aux_t *a) / // initialization m_b = n_b = 0; b = 0; - gmax = zero = _mm_set1_epi32(0); + zero = _mm_set1_epi32(0); gapoe = _mm_set1_epi8(a->gapo + a->gape); gape = _mm_set1_epi8(a->gape); shift = _mm_set1_epi8(q->shift); - thres = _mm_set1_epi8(254 - q->mdiff); // when max score exceeds this, shift all scores by "reduce" below + thres = _mm_set1_epi8(_thres); // when max score exceeds this, shift all scores by "reduce" below reduce = _mm_set1_epi8(127); H0 = q->H0; H1 = q->H1; E = q->E; Hmax = q->Hmax; q->T = a->T; // avoid potential cache miss @@ -113,7 +113,7 @@ int ksw_sse2_16(ksw_query_t *q, int tlen, const uint8_t *target, ksw_aux_t *a) / int j, k, cmp, imax, T = q->T; __m128i e, h, f = zero, max = zero, *S = q->qp + target[i] * slen; // s is the 1st score vector h = _mm_load_si128(H0 + slen - 1); // h={2,5,8,11,14,17,-1,-1} in the above example - h = _mm_slli_si128(h, 1); // h=H(i-1,-1); << instead of >> because x86 is little-endian + h = _mm_slli_si128(h, 1); // h=H(i-1,-1); << instead of >> because x64 is little-endian for (j = 0; LIKELY(j < slen); ++j) { /* SW cells are computed in the following order: * H(i,j) = max{H(i-1,j-1)+S(i,j), E(i,j), F(i,j)} @@ -153,8 +153,9 @@ int ksw_sse2_16(ksw_query_t *q, int tlen, const uint8_t *target, ksw_aux_t *a) / } } end_loop: - __max_16(imax, max); // imax is the maximum number if max - if (imax + sum >= T) { // write the b array + //int k;for (k=0;k<16;++k)printf("%d ", ((uint8_t*)&max)[k]);printf("\n"); + __max_16(imax, max); // imax is the maximum number in max + if (imax + sum >= T) { // write the b array; this condition adds branching unfornately if (n_b == 0 || (uint32_t)b[n_b-1] + 1 != (uint32_t)i) { // then append if (n_b == m_b) { m_b = m_b? m_b<<1 : 8; @@ -162,23 +163,16 @@ end_loop: } b[n_b++] = (uint64_t)(imax + sum)<<32 | i; } else if (b[n_b-1]>>32 < imax + sum) b[n_b-1] = (uint64_t)(imax + sum)<<32 | i; // modify the last - if (_mm_movemask_epi8(_mm_cmpeq_epi8(_mm_subs_epu8(max, gmax), zero)) != 0xffff) { // if max > gmax at any position - int igmax; - __max_16(igmax, gmax); // maximum in gmax - if (imax > igmax) { // if the max has been updated - te = i; // the end position on the target - for (j = 0; LIKELY(j < slen); ++j) // keep the H1 vector - _mm_store_si128(Hmax + j, _mm_load_si128(H1 + j)); - } - } } - gmax = _mm_max_epu8(gmax, max); // update gmax - if (_mm_movemask_epi8(_mm_cmpeq_epi8(_mm_subs_epu8(gmax, thres), zero)) != 0xffff) { // reduce + if (imax > gmax) { + gmax = imax; te = i; // te is the end position on the target + for (j = 0; LIKELY(j < slen); ++j) // keep the H1 vector + _mm_store_si128(Hmax + j, _mm_load_si128(H1 + j)); + } + if (gmax >= _thres) { // reduce // When overflow is going to happen, subtract 127 from all scores. This heuristic // may miss the best alignment, but in practice this should happen very rarely. - sum += 127; - gmax = _mm_subs_epu8(gmax, reduce); - //int k;for (k=0;k<16;++k)printf("%d ", ((uint8_t*)&thres)[k]);printf("\n"); + sum += 127; gmax -= 127; for (j = 0; LIKELY(j < slen); ++j) { h = _mm_subs_epu8(_mm_load_si128(H1 + j), reduce); _mm_store_si128(H1 + j, h); @@ -188,16 +182,15 @@ end_loop: } S = H1; H1 = H0; H0 = S; // swap H0 and H1 } - __max_16(score, gmax); - a->score = score + sum; a->te = te; + a->score = gmax + sum; a->te = te; { // get a->qe, the end of query match int max = -1; uint8_t *t = (uint8_t*)Hmax; - for (i = 0, score = 0, a->qe = -1; i < q->qlen; ++i, ++t) + for (i = 0, a->qe = -1; i < q->qlen; ++i, ++t) if ((int)*t > max) max = *t, a->qe = i / 16 + i % 16 * slen; } free(b); - return a->score < a->T? -1 : a->score; + return a->score; } /******************************************* @@ -284,10 +277,10 @@ int main(int argc, char *argv[]) int s; for (i = 0; i < kst->seq.l; ++i) kst->seq.s[i] = seq_nt4_table[(int)kst->seq.s[i]]; s = ksw_sse2_16(q[0], kst->seq.l, (uint8_t*)kst->seq.s, &a); - if (s >= 0) printf("%s\t%s\t+\t%d\t%d\t%d\n", ksq->name.s, kst->name.s, s, a.te+1, a.qe+1); + printf("%s\t%s\t+\t%d\t%d\t%d\n", ksq->name.s, kst->name.s, s, a.te+1, a.qe+1); if (q[1]) { s = ksw_sse2_16(q[1], kst->seq.l, (uint8_t*)kst->seq.s, &a); - if (s >= 0) printf("%s\t%s\t-\t%d\t%d\t%d\n", ksq->name.s, kst->name.s, s, a.te+1, a.qe+1); + printf("%s\t%s\t-\t%d\t%d\t%d\n", ksq->name.s, kst->name.s, s, a.te+1, a.qe+1); } } free(q[0]); free(q[1]);